Gene: TARBP2

Alternate names for this Gene: LOQS|TRBP|TRBP1|TRBP2

Gene Summary: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.

Gene is located in Chromosome: 12

Location in Chromosome : 12q13.13

Description of this Gene: TARBP2 subunit of RISC loading complex

Type of Gene: protein-coding

Gene: NPFF

Alternate names for this Gene: FMRFAL

Gene Summary: This gene encodes a member of the FMRFamide related peptide (FARP) family of neuropeptides. The encoded preproprotein is proteolytically processed to generate multiple amidated peptides. These peptides may play a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. Patients with hypertension exhibit decreased expression of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Gene is located in Chromosome: 12

Location in Chromosome : 12q13.13

Description of this Gene: neuropeptide FF-amide peptide precursor

Type of Gene: protein-coding

Gene: ATF7-NPFF

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 12

Location in Chromosome : 12q13.13

Description of this Gene: ATF7-NPFF readthrough

Type of Gene: protein-coding