Gene: TCHH

Alternate names for this Gene: THH|THL|TRHY|UHS3

Gene Summary: The protein encoded by this gene forms crosslinked complexes with itself and keratin intermediate filaments to provide mechanical strength to the hair follicle inner root sheath. The encoded protein also is important for structural integrity of the filiform papillae of the tongue. Defects in this gene are a cause of uncombable hair syndrome.

Gene is located in Chromosome: 1

Location in Chromosome : 1q21.3

Description of this Gene: trichohyalin

Type of Gene: protein-coding