Gene: TCTA

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 3

Location in Chromosome : 3p21.31

Description of this Gene: T cell leukemia translocation altered

Type of Gene: protein-coding

Gene: RHOA

Alternate names for this Gene: ARH12|ARHA|EDFAOB|RHO12|RHOH12

Gene Summary: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.

Gene is located in Chromosome: 3

Location in Chromosome : 3p21.31

Description of this Gene: ras homolog family member A

Type of Gene: protein-coding

rs6784820 in TCTA;RHOA gene and Crohn Disease PMID 18587394 2008 Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.