Gene: TEC
Alternate names for this Gene: PSCTK4
Gene Summary: The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
Gene is located in Chromosome: 4
Location in Chromosome : 4p12-p11
Description of this Gene: tec protein tyrosine kinase
Type of Gene: protein-coding