Gene: TEX14

Alternate names for this Gene: CT113|SPGF23

Gene Summary: The protein encoded by this gene is necessary for intercellular bridges in germ cells, which are required for spermatogenesis. Three transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 17

Location in Chromosome : 17q22

Description of this Gene: testis expressed 14, intercellular bridge forming factor

Type of Gene: protein-coding

Gene: RAD51C

Alternate names for this Gene: BROVCA3|FANCO|R51H3|RAD51L2

Gene Summary: This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 17

Location in Chromosome : 17q22

Description of this Gene: RAD51 paralog C

Type of Gene: protein-coding