Gene: TEX15

Alternate names for this Gene: CT42|SPGF25

Gene Summary: This gene encodes a protein that is required for DNA double-strand break repair, chromosome synapsis, and meiotic recombination in spermatocytes. Male mice with a knockout of the orthologous gene are viable but sterile. Loss-of-function mutations in the orthologous mouse gene cause early meiotic arrest in spermatocytes, before the mid-pachytene stage. Naturally occurring mutations in this gene are associated with nonobstructive azoospermia.

Gene is located in Chromosome: 8

Location in Chromosome : 8p12

Description of this Gene: testis expressed 15, meiosis and synapsis associated

Type of Gene: protein-coding

Gene: LOC105379357

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rs116898861 in TEX15;LOC105379357 gene and White Blood Cell Count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.