Gene: TGM3

Alternate names for this Gene: TGE|UHS2

Gene Summary: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle.

Gene is located in Chromosome: 20

Location in Chromosome : 20p13

Description of this Gene: transglutaminase 3

Type of Gene: protein-coding

Gene: LOC105372503

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

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rs214782 in TGM3;LOC105372503 gene and Basal Cell Cancer PMID 25855136 2015 New basal cell carcinoma susceptibility loci.

PMID 24403052 2014 Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma.

PMID 27539887 2016 Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma.

rs214782 in TGM3;LOC105372503 gene and Basal Cell Neoplasm PMID 25855136 2015 New basal cell carcinoma susceptibility loci.

PMID 24403052 2014 Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma.

PMID 27539887 2016 Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma.

rs214782 in TGM3;LOC105372503 gene and Basal cell carcinoma PMID 25855136 2015 New basal cell carcinoma susceptibility loci.

PMID 24403052 2014 Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma.

PMID 27539887 2016 Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma.

rs214782 in TGM3;LOC105372503 gene and Carcinoma, Basal Cell PMID 24403052 2014 Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma.