Gene: TGM3

Alternate names for this Gene: TGE|UHS2

Gene Summary: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle.

Gene is located in Chromosome: 20

Location in Chromosome : 20p13

Description of this Gene: transglutaminase 3

Type of Gene: protein-coding