Gene: THAP11

Alternate names for this Gene: CTG-B43a|CTG-B45d|HRIHFB2206|RONIN

Gene Summary: The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases.

Gene is located in Chromosome: 16

Location in Chromosome : 16q22.1

Description of this Gene: THAP domain containing 11

Type of Gene: protein-coding

Gene: CENPT

Alternate names for this Gene: C16orf56|CENP-T|SSMGA

Gene Summary: The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPT is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK056097.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000562787.6/ ENSP00000457810.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

Gene is located in Chromosome: 16

Location in Chromosome : 16q22.1

Description of this Gene: centromere protein T

Type of Gene: protein-coding