Gene: THBS1

Alternate names for this Gene: THBS|THBS-1|TSP|TSP-1|TSP1

Gene Summary: The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.

Gene is located in Chromosome: 15

Location in Chromosome : 15q14

Description of this Gene: thrombospondin 1

Type of Gene: protein-coding

rs1478604 in THBS1 gene and Uric acid measurement (procedure) PMID 31578528 2019 Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.