Gene: TLE3

Alternate names for this Gene: ESG|ESG3|GRG3|HsT18976

Gene Summary: This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Gene is located in Chromosome: 15

Location in Chromosome : 15q23

Description of this Gene: TLE family member 3, transcriptional corepressor

Type of Gene: protein-coding

Gene: LOC105370877

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