Gene: TMC8

Alternate names for this Gene: EV2|EVER2|EVIN2

Gene Summary: Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs.

Gene is located in Chromosome: 17

Location in Chromosome : 17q25.3

Description of this Gene: transmembrane channel like 8

Type of Gene: protein-coding

Gene: TMC6

Alternate names for this Gene: EV1|EVER1|EVIN1|LAK-4P|TNRC6C-AS1|lnc

Gene Summary: Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs.

Gene is located in Chromosome: 17

Location in Chromosome : 17q25.3

Description of this Gene: transmembrane channel like 6

Type of Gene: protein-coding