Gene: TMED10

Alternate names for this Gene: P24(DELTA)|S31I125|S31III125|TMP21|Tmp-21-I|p23|p24d1

Gene Summary: This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

Gene is located in Chromosome: 14

Location in Chromosome : 14q24.3

Description of this Gene: transmembrane p24 trafficking protein 10

Type of Gene: protein-coding