Gene: TMEM181

Alternate names for this Gene: GPR178|KIAA1423

Gene Summary: The TMEM181 gene encodes a putative G protein-coupled receptor expressed on the cell surface (Carette et al., 2009 [PubMed 19965467]; Wollscheid et al., 2009 [PubMed 19349973]).[supplied by OMIM, Jan 2010]. ##Evidence-Data-START## Transcript exon combination :: AB037844.1, SRR1803615.85188.1 [ECO:0000332] ##Evidence-Data-END##

Gene is located in Chromosome: 6

Location in Chromosome : 6q25.3

Description of this Gene: transmembrane protein 181

Type of Gene: protein-coding

rs4709212 in TMEM181 gene and Glaucoma, Open-Angle PMID 29891935 2018 A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci.

rs9364973 in TMEM181 gene and Tonometry PMID 29785010 2018 Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma.