Gene: TMIGD3

Alternate names for this Gene: AD026

Gene Summary: This gene encodes a transmembrane and immunoglobulin domain-containing protein. Alternative splicing results in multiple transcript variants, one of which shares its 5' terminal exon with that of the overlapping adenosine A3 receptor gene (GeneID:140), thus resulting in a fusion product.

Gene is located in Chromosome: 1

Location in Chromosome : 1p13.2

Description of this Gene: transmembrane and immunoglobulin domain containing 3

Type of Gene: protein-coding

Gene: RAP1A

Alternate names for this Gene: C21KG|G-22K|KREV-1|KREV1|RAP1|SMGP21

Gene Summary: This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 1

Location in Chromosome : 1p13.2

Description of this Gene: RAP1A, member of RAS oncogene family

Type of Gene: protein-coding