Gene: TMPRSS15
Alternate names for this Gene: ENTK|PRSS7
Gene Summary: This gene encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive.
Gene is located in Chromosome: 21
Location in Chromosome : 21q21.1
Description of this Gene: transmembrane serine protease 15
Type of Gene: protein-coding