Gene: TNFRSF10A

Alternate names for this Gene: APO2|CD261|DR4|TRAILR-1|TRAILR1

Gene Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.

Gene is located in Chromosome: 8

Location in Chromosome : 8p21.3

Description of this Gene: TNF receptor superfamily member 10a

Type of Gene: protein-coding

Gene: LOC389641

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

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rs79037040 in TNFRSF10A;LOC389641 gene and Age related macular degeneration PMID 26691988 2016 A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.

rs79037040 in TNFRSF10A;LOC389641 gene and Exudative age-related macular degeneration PMID 26691988 2016 A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.

rs79037040 in TNFRSF10A;LOC389641 gene and Geographic Atrophy PMID 26691988 2016 A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.

rs79037040 in TNFRSF10A;LOC389641 gene and exudative macular degeneration PMID 26691988 2016 A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.