Gene: TNIK

Alternate names for this Gene: MRT54

Gene Summary: Wnt signaling plays important roles in carcinogenesis and embryonic development. The protein encoded by this gene is a serine/threonine kinase that functions as an activator of the Wnt signaling pathway. Mutations in this gene are associated with an autosomal recessive form of cognitive disability. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene is located in Chromosome: 3

Location in Chromosome : 3q26.2-q26.31

Description of this Gene: TRAF2 and NCK interacting kinase

Type of Gene: protein-coding

Gene: LOC105374216

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

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Description of this Gene:

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rs9810566 in TNIK;LOC105374216 gene and Adolescent idiopathic scoliosis PMID 28334814 2017 Genome-wide association study identifies novel susceptible loci and highlights Wnt/beta-catenin pathway in the development of adolescent idiopathic scoliosis.

rs115419280 in TNIK;LOC105374216 gene and Duration of sleep PMID 27126917 2016 Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.

rs9810566 in TNIK;LOC105374216 gene and SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 PMID 28334814 2017 Genome-wide association study identifies novel susceptible loci and highlights Wnt/beta-catenin pathway in the development of adolescent idiopathic scoliosis.