Gene: TNNI3K

Alternate names for this Gene: CARK|CCDD

Gene Summary: This gene encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. The protein contains ankyrin repeat, protein kinase and serine-rich domains and is thought to play a role in cardiac physiology.

Gene is located in Chromosome: 1

Location in Chromosome : 1p31.1

Description of this Gene: TNNI3 interacting kinase

Type of Gene: protein-coding

Gene: FPGT-TNNI3K

Alternate names for this Gene: CARK|TNNI3K

Gene Summary: This locus represents naturally occurring read-through transcription from the neighboring fucose-1-phosphate guanylyltransferase (FPGT) and TNNI3 interacting kinase (TNNI3K) genes. Alternative splicing results in multiple transcript variants that are composed of in-frame exons from each individual gene.

Gene is located in Chromosome: 1

Location in Chromosome : 1p31.1

Description of this Gene: FPGT-TNNI3K readthrough

Type of Gene: protein-coding

Gene: LRRC53

Alternate names for this Gene:

Gene Summary:

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rs12041852 in TNNI3K;FPGT-TNNI3K;LRRC53 gene and Body mass index PMID 26604143 2016 Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index.

PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

rs113313252 in TNNI3K;FPGT-TNNI3K;LRRC53 gene and Body mass index procedure PMID 23669352 2013 Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.

rs113313252 in TNNI3K;FPGT-TNNI3K;LRRC53 gene and Finding of body mass index PMID 23669352 2013 Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.

rs1514177 in TNNI3K;FPGT-TNNI3K;LRRC53 gene and Obesity PMID 23563607 2013 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.

rs61778068 in TNNI3K;FPGT-TNNI3K;LRRC53 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.