Gene: TNNI3K

Alternate names for this Gene: CARK|CCDD

Gene Summary: This gene encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. The protein contains ankyrin repeat, protein kinase and serine-rich domains and is thought to play a role in cardiac physiology.

Gene is located in Chromosome: 1

Location in Chromosome : 1p31.1

Description of this Gene: TNNI3 interacting kinase

Type of Gene: protein-coding

Gene: LRRC53

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: FPGT-TNNI3K

Alternate names for this Gene: CARK|TNNI3K

Gene Summary: This locus represents naturally occurring read-through transcription from the neighboring fucose-1-phosphate guanylyltransferase (FPGT) and TNNI3 interacting kinase (TNNI3K) genes. Alternative splicing results in multiple transcript variants that are composed of in-frame exons from each individual gene.

Gene is located in Chromosome: 1

Location in Chromosome : 1p31.1

Description of this Gene: FPGT-TNNI3K readthrough

Type of Gene: protein-coding

rs7514705 in TNNI3K;LRRC53;FPGT-TNNI3K gene and Age at menarche PMID 25231870 2014 Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.

rs12566985 in TNNI3K;LRRC53;FPGT-TNNI3K gene and Body mass index PMID 26604143 2016 Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index.

PMID 28892062 2017 Genome-wide association study identifies 112 new loci for body mass index in the Japanese population.

PMID 25673413 2015 Genetic studies of body mass index yield new insights for obesity biology.

PMID 28443625 2017 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

PMID 23669352 2013 Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.

PMID 20935630 2010 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

rs12142020 in TNNI3K;LRRC53;FPGT-TNNI3K gene and Body mass index procedure PMID 23669352 2013 Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.

PMID 23001569 2013 Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals.

PMID 20935630 2010 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

rs12142020 in TNNI3K;LRRC53;FPGT-TNNI3K gene and Finding of body mass index PMID 23669352 2013 Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.

PMID 20935630 2010 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

PMID 23001569 2013 Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals.

rs12566985 in TNNI3K;LRRC53;FPGT-TNNI3K gene and Smoking PMID 28443625 2017 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

PMID 30643258 2019 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.