Gene: TOM1

Alternate names for this Gene: -

Gene Summary: This gene was identified as a target of the v-myb oncogene. The encoded protein shares its N-terminal domain in common with proteins associated with vesicular trafficking at the endosome. It is recruited to the endosomes by its interaction with endofin. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 22

Location in Chromosome : 22q12.3

Description of this Gene: target of myb1 membrane trafficking protein

Type of Gene: protein-coding

rs138740 in TOM1 gene and Monoclonal Gammopathy of Undetermined Significance PMID 26007630 2015 Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma.

rs138740 in TOM1 gene and Multiple Myeloma PMID 26007630 2015 Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma.

PMID 27363682 2016 Genome-wide association study identifies multiple susceptibility loci for multiple myeloma.

rs138740 in TOM1 gene and Paraproteinemias PMID 26007630 2015 Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma.

rs138777 in TOM1 gene and Serum total cholesterol measurement PMID 28334899 2017 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.

PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.