Gene: TOPBP1

Alternate names for this Gene: Dpb11|TOP2BP1

Gene Summary: This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.

Gene is located in Chromosome: 3

Location in Chromosome : 3q22.1

Description of this Gene: DNA topoisomerase II binding protein 1

Type of Gene: protein-coding

rs10935070 in TOPBP1 gene and Alcohol consumption PMID 21665994 2011 Genome-wide association study identifies two loci strongly affecting transferrin glycosylation.