Gene: TRAF3IP2

Alternate names for this Gene: ACT1|C6orf2|C6orf4|C6orf5|C6orf6|CANDF8|CIKS|PSORS13

Gene Summary: This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.

Gene is located in Chromosome: 6

Location in Chromosome : 6q21

Description of this Gene: TRAF3 interacting protein 2

Type of Gene: protein-coding

Gene: TRAF3IP2-AS1

Alternate names for this Gene: C6UAS|C6orf3|NCRNA00248|TRAF3IP2-AS2

Gene Summary:

Gene is located in Chromosome: 6

Location in Chromosome : 6q21

Description of this Gene: TRAF3IP2 antisense RNA 1

Type of Gene: ncRNA