Gene: TRDN

Alternate names for this Gene: CPVT5|TDN|TRISK

Gene Summary: This gene encodes an integral membrane protein that contains a single transmembrane domain. As similar protein in rabbits plays a role in skeletal muscle excitation-contraction coupling as part of the calcium release complex in association with the ryanodine receptor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and single nucleotide polymorphisms in this gene may be markers for IgA nephritis.

Gene is located in Chromosome: 6

Location in Chromosome : 6q22.31

Description of this Gene: triadin

Type of Gene: protein-coding

rs1085307100 in TRDN gene and VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 5, WITH OR WITHOUT MUSCLE WEAKNESS PMID 22422768 2012 Absence of triadin, a protein of the calcium release complex, is responsible for cardiac arrhythmia with sudden death in human.