Gene: TREML1

Alternate names for this Gene: GLTL1825|PRO3438|TLT-1|TLT1|dJ238O23.3

Gene Summary: This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.1

Description of this Gene: triggering receptor expressed on myeloid cells like 1

Type of Gene: protein-coding

Gene: LOC105375056

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

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Type of Gene:

Gene: TREM2

Alternate names for this Gene: PLOSL2|TREM-2|Trem2a|Trem2b|Trem2c

Gene Summary: This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.1

Description of this Gene: triggering receptor expressed on myeloid cells 2

Type of Gene: protein-coding

rs7748513 in TREML1;LOC105375056;TREM2 gene and C-reactive protein measurement PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.

PMID 22939635 2012 Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women.