Gene: TRIM11

Alternate names for this Gene: BIA1|RNF92

Gene Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nucleus and the cytoplasm. Its function has not been identified.

Gene is located in Chromosome: 1

Location in Chromosome : 1q42.13

Description of this Gene: tripartite motif containing 11

Type of Gene: protein-coding

Gene: MIR6742

Alternate names for this Gene: hsa-mir-6742

Gene Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Gene is located in Chromosome: 1

Location in Chromosome : 1q42.13

Description of this Gene: microRNA 6742

Type of Gene: ncRNA

rs564309 in TRIM11;MIR6742 gene and Progressive supranuclear palsy PMID 30066433 2018 Variation at the TRIM11 locus modifies progressive supranuclear palsy phenotype.