Gene: TRPM8

Alternate names for this Gene: LTRPC6|LTrpC-6|TRPP8|trp-p8

Gene Summary:

Gene is located in Chromosome: 2

Location in Chromosome : 2q37.1

Description of this Gene: transient receptor potential cation channel subfamily M member 8

Type of Gene: protein-coding

rs10490012 in TRPM8 gene and Bilirubin measurement PMID 31319653 2019 A total of 5 genetic variants-TRPM8 (rs10490012), USP40 (rs12993249), ATG16L1 (rs2119503), SLCO1B1 (rs4149014), and SLCO1B3 (rs73233620)-were selected as genetic instruments for serum bilirubin levels using a communitybased cohort, the Korean Genome and Epidemiology Study, comprising 33,598 subjects.

rs10166942 in TRPM8 gene and Common Migraine PMID 23793025 2013 Genome-wide meta-analysis identifies new susceptibility loci for migraine.

rs2362290 in TRPM8 gene and Headache PMID 29397368 2018 A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N=223,773).

rs10166942 in TRPM8 gene and Migraine Disorders PMID 27322543 2016 Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.

PMID 22683712 2012 Genome-wide association analysis identifies susceptibility loci for migraine without aura.

PMID 21666692 2011 The associations at rs2651899 and rs10166942 were specific for migraine compared with non-migraine headache.

PMID 23793025 2013 Genome-wide meta-analysis identifies new susceptibility loci for migraine.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

rs6741751 in TRPM8 gene and Migraine with Aura PMID 23793025 2013 Genome-wide meta-analysis identifies new susceptibility loci for migraine.