Gene: TSPAN31

Alternate names for this Gene: SAS

Gene Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma.

Gene is located in Chromosome: 12

Location in Chromosome : 12q14.1

Description of this Gene: tetraspanin 31

Type of Gene: protein-coding

Gene: AGAP2

Alternate names for this Gene: CENTG1|GGAP2|PIKE

Gene Summary: The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene is located in Chromosome: 12

Location in Chromosome : 12q14.1

Description of this Gene: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

Type of Gene: protein-coding