Gene: TSPEAR
Alternate names for this Gene: C21orf29|DFNB98|ECTD14|TSP-EAR
Gene Summary: This gene encodes a protein that contains a N-terminal thrombospondin-type laminin G domain and several tandem arranged epilepsy-associated repeats (EARs). A mutation in this gene is the cause of autosomal recessive deafness-98. Alternate splicing results in multiple transcript variants.
Gene is located in Chromosome: 21
Location in Chromosome : 21q22.3
Description of this Gene: thrombospondin type laminin G domain and EAR repeats
Type of Gene: protein-coding
rs139455627 in
TSPEAR gene and
Abnormal posture
PMID 27736875 2016 Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis.
rs139455627 in
TSPEAR gene and
Abnormality of the dentition
PMID 27736875 2016 Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis.
rs139455627 in
TSPEAR gene and
Delayed speech and language development
PMID 27736875 2016 Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis.
rs139455627 in
TSPEAR gene and
Dyskinetic syndrome
PMID 27736875 2016 Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis.
rs139455627 in
TSPEAR gene and
Dystonia
PMID 27736875 2016 Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis.
rs139455627 in
TSPEAR gene and
Impaired cognition
PMID 27736875 2016 Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis.
rs139455627 in
TSPEAR gene and
Maternal seizures
PMID 27736875 2016 Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis.
rs139455627 in
TSPEAR gene and
Muscular hypotonia of the trunk
PMID 27736875 2016 Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis.
rs139455627 in
TSPEAR gene and
Sagittal craniosynostosis
PMID 27736875 2016 Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis.
rs139455627 in
TSPEAR gene and
Seizures
PMID 27736875 2016 Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis.
rs139455627 in
TSPEAR gene and
Slurred speech
PMID 27736875 2016 Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis.
rs139455627 in
TSPEAR gene and
Taurodontism
PMID 27736875 2016 Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis.
rs139455627 in
TSPEAR gene and
Tooth absent
PMID 27736875 2016 Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis.
rs139455627 in
TSPEAR gene and
Widely spaced teeth
PMID 27736875 2016 Mutations in TSPEAR, Encoding a Regulator of Notch Signaling, Affect Tooth and Hair Follicle Morphogenesis.