Gene: TTC36

Alternate names for this Gene: HBP21

Gene Summary: The protein encoded by this gene has three tetratricopeptide repeats and is a chaperone for heat shock protein 70. The encoded protein may function as a tumor suppressor in hepatocellular carcinoma (HCC) since it promotes apoptosis but is downregulated in HCC.

Gene is located in Chromosome: 11

Location in Chromosome : 11q23.3

Description of this Gene: tetratricopeptide repeat domain 36

Type of Gene: protein-coding

Gene: LOC101929089

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 11

Location in Chromosome : 11q23.3

Description of this Gene: uncharacterized LOC101929089

Type of Gene: ncRNA

Gene: KMT2A

Alternate names for this Gene: ALL-1|CXXC7|HRX|HTRX1|MLL|MLL1|MLL1A|TRX1|WDSTS

Gene Summary: This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Multiple chromosomal translocations involving this gene are the cause of certain acute lymphoid leukemias and acute myeloid leukemias. Alternate splicing results in multiple transcript variants.

Gene is located in Chromosome: 11

Location in Chromosome : 11q23.3

Description of this Gene: lysine methyltransferase 2A

Type of Gene: protein-coding