Gene: TTC4

Alternate names for this Gene: CNS1

Gene Summary: This gene encodes a protein that contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions and chaperone activity. The encoded protein interacts with heat shock proteins 70 and 90. Alternative splicing results in multiple transcript variants. Naturally-occuring readthrough transcription occurs from upstream gene MROH (maestro heat-like repeat family member 7) to this gene.

Gene is located in Chromosome: 1

Location in Chromosome : 1p32.3

Description of this Gene: tetratricopeptide repeat domain 4

Type of Gene: protein-coding

Gene: MROH7-TTC4

Alternate names for this Gene: C1orf175|HEATR8|HEATR8-TTC4|MROH7

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring MROH7 (maestro heat-like repeat family member 7) and TTC4 (tetratricopeptide repeat domain 4) genes. Alternative splicing results in multiple transcript variants, which are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to produce protein products.

Gene is located in Chromosome: 1

Location in Chromosome : 1p32.3

Description of this Gene: MROH7-TTC4 readthrough (NMD candidate)

Type of Gene: ncRNA

rs61768793 in TTC4;MROH7-TTC4 gene and Serum albumin measurement PMID 22286219 2012 Genome-wide association study identifies multiple loci influencing human serum metabolite levels.