Gene: TTI2

Alternate names for this Gene: C8orf41|MRT39

Gene Summary: This gene encodes a regulator of the DNA damage response. The protein is a component of the Triple T complex (TTT) which also includes telomere length regulation protein and TELO2 interacting protein 1. The TTT complex is involved in cellular resistance to DNA damage stresses and may act as a regulator of phosphoinositide-3-kinase-related protein kinase (PIKK) abundance.

Gene is located in Chromosome: 8

Location in Chromosome : 8p12

Description of this Gene: TELO2 interacting protein 2

Type of Gene: protein-coding

rs10094645 in TTI2 gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs7841518 in TTI2 gene and Lymphocyte Count measurement PMID 22286170 2012 The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes.