Gene: TUB

Alternate names for this Gene: RDOB|rd5

Gene Summary: This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene is located in Chromosome: 11

Location in Chromosome : 11p15.4

Description of this Gene: TUB bipartite transcription factor

Type of Gene: protein-coding

Gene: RIC3

Alternate names for this Gene: AYST720|PRO1385

Gene Summary: This gene encodes a member of the resistance to inhibitors of cholinesterase 3-like family which functions as a chaperone of specific 5-hydroxytryptamine type 3 receptor and nicotinic acetylcholine receptor subtypes. The encoded protein influences the folding and assembly of these receptor subunits in the endoplasmic reticulum and expression on the cell surface. This protein contains an N-terminal transmembrane domain, a proline-rich spacer, and a cytosolic C-terminal coiled-coil domain. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 11

Location in Chromosome : 11p15.4

Description of this Gene: RIC3 acetylcholine receptor chaperone

Type of Gene: protein-coding