Gene: TYRO3

Alternate names for this Gene: BYK|Dtk|Etk-2|RSE|Rek|Sky|Tif

Gene Summary: The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.

Gene is located in Chromosome: 15

Location in Chromosome : 15q15.1

Description of this Gene: TYRO3 protein tyrosine kinase

Type of Gene: protein-coding

rs2289743 in TYRO3 gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs3784283 in TYRO3 gene and Microalbuminuria PMID 31511532 2019 Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.