Gene: UBE2E1

Alternate names for this Gene: UBCH6

Gene Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene is located in Chromosome: 3

Location in Chromosome : 3p24.2

Description of this Gene: ubiquitin conjugating enzyme E2 E1

Type of Gene: protein-coding

Gene: UBE2E1-AS1

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Gene Summary:

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rs3762767 in UBE2E1;UBE2E1-AS1 gene and Intelligence PMID 29326435 2019 A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.