Gene: UBE2R2

Alternate names for this Gene: CDC34B|E2-CDC34B|UBC3B

Gene Summary: Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.

Gene is located in Chromosome: 9

Location in Chromosome : 9p13.3

Description of this Gene: ubiquitin conjugating enzyme E2 R2

Type of Gene: protein-coding