Gene: UCK2

Alternate names for this Gene: TSA903|UK|UMPK

Gene Summary: This gene encodes a pyrimidine ribonucleoside kinase. The encoded protein (EC 2.7.1.48) catalyzes phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively.

Gene is located in Chromosome: 1

Location in Chromosome : 1q24.1

Description of this Gene: uridine-cytidine kinase 2

Type of Gene: protein-coding

rs3790672 in UCK2 gene and Testicular Germ Cell Tumor PMID 23666240 2013 Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14.

PMID 25877299 2015 Two new loci and gene sets related to sex determination and cancer progression are associated with susceptibility to testicular germ cell tumor.

PMID 28604732 2017 Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor.

PMID 28604728 2017 Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor.

rs3790672 in UCK2 gene and Testicular Neoplasms PMID 23666240 2013 Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14.