Gene: VDAC1

Alternate names for this Gene: PORIN|VDAC-1

Gene Summary: This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.

Gene is located in Chromosome: 5

Location in Chromosome : 5q31.1

Description of this Gene: voltage dependent anion channel 1

Type of Gene: protein-coding

rs247459 in VDAC1 gene and Alopecia Areata PMID 25608926 2015 Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci.