Gene: VPS54

Alternate names for this Gene: HCC8|PPP1R164|SLP-8p|VPS54L|WR|hVps54L

Gene Summary: This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms

Gene is located in Chromosome: 2

Location in Chromosome : 2p15-p14

Description of this Gene: VPS54 subunit of GARP complex

Type of Gene: protein-coding

rs13014371 in VPS54 gene and Diastolic blood pressure PMID 30224653 2018 Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

rs13014029 in VPS54 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.