Gene: VRK3

Alternate names for this Gene: -

Gene Summary: This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.33

Description of this Gene: VRK serine/threonine kinase 3

Type of Gene: protein-coding