Gene: VTN

Alternate names for this Gene: V75|VN|VNT

Gene Summary: The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.

Gene is located in Chromosome: 17

Location in Chromosome : 17q11.2

Description of this Gene: vitronectin

Type of Gene: protein-coding

Gene: SARM1

Alternate names for this Gene: HsTIR|MyD88-5|SAMD2|SARM|hSARM1

Gene Summary:

Gene is located in Chromosome: 17

Location in Chromosome : 17q11.2

Description of this Gene: sterile alpha and TIR motif containing 1

Type of Gene: protein-coding

rs704 in VTN;SARM1 gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.

PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs704 in VTN;SARM1 gene and Low density lipoprotein cholesterol measurement PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.

PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.

PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.

rs704 in VTN;SARM1 gene and Osteoprotegerin test PMID 25080503 2014 Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels.