Gene: WNT10A

Alternate names for this Gene: OODD|SSPS|STHAG4

Gene Summary: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region.

Gene is located in Chromosome: 2

Location in Chromosome : 2q35

Description of this Gene: Wnt family member 10A

Type of Gene: protein-coding

Gene: LOC105373882

Alternate names for this Gene:

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rs72966077 in WNT10A;LOC105373882 gene and Acne Vulgaris PMID 30542056 2018 Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne.