Gene: WWC1

Alternate names for this Gene: HBEBP3|HBEBP36|KIBRA|MEMRYQTL|PPP1R168

Gene Summary: The protein encoded by this gene is a cytoplasmic phosphoprotein that interacts with PRKC-zeta and dynein light chain-1. Alleles of this gene have been found that enhance memory in some individuals. Three transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 5

Location in Chromosome : 5q34

Description of this Gene: WW and C2 domain containing 1

Type of Gene: protein-coding

rs1965673 in WWC1 gene and Behcet Syndrome PMID 23041938 2013 Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease.

rs11134512 in WWC1 gene and Body mass index PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs12522956 in WWC1 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

rs78954674 in WWC1 gene and Microalbuminuria PMID 30566433 2018 A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes.