Gene: XKR4

Alternate names for this Gene: XRG4

Gene Summary:

Gene is located in Chromosome: 8

Location in Chromosome : 8q12.1

Description of this Gene: XK related 4

Type of Gene: protein-coding

rs2622590 in XKR4 gene and Blood thyroid stimulating hormone analysis PMID 24852370 2014 Genome-wide association study identifies a novel susceptibility gene for serum TSH levels in Chinese populations.

rs12542677 in XKR4 gene and Cytokine Measurement PMID 22610502 2012 Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.

rs10101279 in XKR4 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

rs2622590 in XKR4 gene and Thyroid stimulating hormone measurement PMID 24852370 2014 The rs2622590_T allele at XKR4 and the rs925489_C allele near FOXE1 were correlated with low TSH levels and were found to be nominally associated to patients with papillary thyroid carcinoma (PTC) (OR = 1.41, P= 0.014 for rs2622590_T, and OR = 1.61, P= 0.030 for rs925489_C).