Gene: YY1

Alternate names for this Gene: DELTA|GADEVS|INO80S|NF-E1|UCRBP|YIN-YANG-1

Gene Summary: YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.

Gene is located in Chromosome: 14

Location in Chromosome : 14q32.2

Description of this Gene: YY1 transcription factor

Type of Gene: protein-coding

rs7153665 in YY1 gene and Secondary malignant neoplasm of colon and/or rectum PMID 30738427 2019 A genome-wide association study identifies single nucleotide polymorphisms associated with time-to-metastasis in colorectal cancer.