Gene: ZBTB16

Alternate names for this Gene: PLZF|ZNF145

Gene Summary: This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.

Gene is located in Chromosome: 11

Location in Chromosome : 11q23.2

Description of this Gene: zinc finger and BTB domain containing 16

Type of Gene: protein-coding

Gene: LOC101928875

Alternate names for this Gene:

Gene Summary:

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rs648044 in ZBTB16;LOC101928875 gene and Central Nervous System Neoplasms PMID 26424050 2015 Genome-wide association study identifies multiple susceptibility loci for glioma.

PMID 28346443 2017 Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.

rs648044 in ZBTB16;LOC101928875 gene and Glioma PMID 26424050 2015 Genome-wide association study identifies multiple susceptibility loci for glioma.

PMID 28346443 2017 Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.