Gene: ZBTB25

Alternate names for this Gene: C14orf51|KUP|ZNF46

Gene Summary:

Gene is located in Chromosome: 14

Location in Chromosome : 14q23.3

Description of this Gene: zinc finger and BTB domain containing 25

Type of Gene: protein-coding

Gene: MTHFD1

Alternate names for this Gene: CIMAH|MTHFC|MTHFD

Gene Summary: This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.

Gene is located in Chromosome: 14

Location in Chromosome : 14q23.3

Description of this Gene: methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1

Type of Gene: protein-coding