Gene: ZFP91-CNTF

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: ZFP91

Alternate names for this Gene: DMS-8|DSM-8|FKSG11|PZF|ZFP-91|ZNF757

Gene Summary: The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. This protein functions as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. Alternative splicing results in multiple transcript variants. A read-through transcript variant composed of ZFP91 and the downstream CNTF gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. A ZFP91-related pseudogene has also been identified on chromosome 2.

Gene is located in Chromosome: 11

Location in Chromosome : 11q12.1

Description of this Gene: ZFP91 zinc finger protein, atypical E3 ubiquitin ligase

Type of Gene: protein-coding

rs948562 in ZFP91-CNTF;ZFP91 gene and Lymphoma PMID 23349640 2013 Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies.

rs7102852 in ZFP91-CNTF;ZFP91 gene and Systolic Pressure PMID 30578418 2019 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.