Gene: ZMAT3

Alternate names for this Gene: PAG608|WIG-1|WIG1

Gene Summary: This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid.

Gene is located in Chromosome: 3

Location in Chromosome : 3q26.32

Description of this Gene: zinc finger matrin-type 3

Type of Gene: protein-coding

rs7641761 in ZMAT3 gene and Finding of Mean Corpuscular Hemoglobin PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs753173864 in ZMAT3 gene and Mean Corpuscular Volume (result) PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.