Gene: ZNF365

Alternate names for this Gene: Su48|UAN|ZNF365D

Gene Summary: This gene encodes a zinc finger protein that may play a role in the repair of DNA damage and maintenance of genome stability. The N-terminal C2H2 zinc finger motif is required to form a protein complex with PARP1 and MRE11, which are known to be involved in the restart of stalled DNA replication forks. A mutation in this gene may be associated with breast cancer susceptibility.

Gene is located in Chromosome: 10

Location in Chromosome : 10q21.2

Description of this Gene: zinc finger protein 365

Type of Gene: protein-coding

Gene: LOC105378327

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

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rs10995245 in ZNF365;LOC105378327 gene and Asthma PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs10995255 in ZNF365;LOC105378327 gene and Basal Cell Cancer PMID 31174203 2019 Combined analysis of keratinocyte cancers identifies novel genome-wide loci.

rs10995255 in ZNF365;LOC105378327 gene and Basal Cell Neoplasm PMID 31174203 2019 Combined analysis of keratinocyte cancers identifies novel genome-wide loci.

rs10995255 in ZNF365;LOC105378327 gene and Basal cell carcinoma PMID 31174203 2019 Combined analysis of keratinocyte cancers identifies novel genome-wide loci.

rs10995245 in ZNF365;LOC105378327 gene and Childhood asthma PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs7076156 in ZNF365;LOC105378327 gene and Crohn Disease PMID 22412388 2012 A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.

rs10995245 in ZNF365;LOC105378327 gene and Narcolepsy PMID 24204295 2013 Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic.

PMID 23459209 2013 ImmunoChip study implicates antigen presentation to T cells in narcolepsy.

rs7071642 in ZNF365;LOC105378327 gene and Psoriasis PMID 22482804 2012 Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci.

rs10995249 in ZNF365;LOC105378327 gene and White Blood Cell Count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.